教員情報 - 村木克彦 | 愛知学院大学

ムラキカツヒコ MURAKI Katsuhiko
村木克彦

所属薬学部薬効解析学

職種教授

著書・論文歴
2024/07	論文	Novel characterization of endogenous transient receptor potential melastatin 3 ion channels from Gulf War Illness participants. Plos One 19 (6),e0305704 (共著)
2024/06	論文	Critical Amino Acid Residues Regulating TRPA1 Zn2+ Response: A Comparative Study Across Species. J.Biol.Chem. 300 (6),107302 (共著)
2024/06	論文	Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 condition: a potential pharmacotherapeutic target. Front. Immunol. 15,1264702 (共著)
2024/06	論文	Thomas (Tom) B. Bolton - a major force in smooth muscle research J. Physiol. in press (共著)
2022	論文	Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of myalgic encephalomyelitis/chronic fatigue syndrome patients J Trans Med 20,94 (共著)
2022	論文	Potent Activation of Human but Not Mouse TRPA1 by JT010. Int. J. Mol. Sci. 23 ((22)),1429 (共著)
2022	論文	Transient receptor potential melastatin 3 dysfunction in post COVID-19 condition and myalgic encephalomyelitis/chronic fatigue syndrome patients. Mol Med 28 (1),98 (共著)
2021	論文	HIF-1α dependent upregulation of ZIP8, ZIP14, and TRPA1 modify intracellular Zn2+ accumulation in inflammatory synoviocytes. Int. J. Mol. Sci 22 (12),6349 (共著)
2021	論文	Potential therapeutic benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of Transient Receptor Potential Melastatin 3 ion channels in pathophysiology and treatment. Frontiers in Immunol. 12,687806 (共著)
2021	論文	The Inflammatory Regulation of TRPA1 Expression in Human A549 Lung Epithelial Cells. Pulm Pharmacol Ther 70,102059 (共著)
2019	著書	TRPC1／4／5チャネルの生理機能および疾病との関連と標的創薬―特異的な活性化薬・抑制薬の発見による研究展開医学のあゆみ 270 (10),889-895頁 (共著)
2019	論文	Mechanically-activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase and interleukin-6 secretion. J. Biol. Chem. 294 (46),17395-17408頁 (共著)
2019	論文	Naltrexone restores impaired transient receptor potential melastatin 3 ion channel function in natural killer cells from myalgic encephalomyelitis/chronic fatigue syndrome patients Frontiers in Immunol. 10,2545 (共著)
2019	論文	PIEZO1 and TRPV4, which are distinct mechano-sensors in the osteoblastic MC3T3-E1 cells, modify the cell-proliferation Int. J. Mol. Sci. 20 (19),e4960 (共著)
2019	論文	Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Sci. Rep. 9 (1),16876 (共著)
2019	論文	Potent, selective and subunit-dependent activation of TRPC5 channels by a xanthine derivative. Brit. J. Pharmacol. 176,3924-3938頁 (共著)
2019	論文	Pyrazine-fused triterpenoids block the TRPA1 ion channel in vitro and inhibit TRPA1-mediated acute inflammation in vivo. ACS Chem Neurosci. (共著)
2019	論文	Regulation of NRF2, AP-1, and NF-KB by cigarette smoke exposure in three-dimensional human bronchial epithelial cells. J. Appl. Toxicol. 39,717-725頁 (共著)
2019	論文	Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in Natural Killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients. Mol Med (共著)
2018	論文	Loss of Transient Receptor Potential Melastatin 3 ion channel function in natural killer cells from Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients. Mol Med 24 (1),44 (共著)
2018	論文	PIEZO1 channel is a potential regulator of synovial sarcoma cell-viability Int. J. Mol. Sci. 19 (5),e1452 (共著)
2018	論文	Remarkable progress with small-molecule modulation of TRPC1/4/5 channels: Implications for understanding the channels in health and disease. Cells 7 (6),e52 (共著)
2017	論文	(-)-Englerin A-evoked Cytotoxicity is Mediated by Na⁺ Influx and Counteracted by Na⁺ /K⁺-ATPase. J. Biol. Chem. 292,723-731頁 (共著)
2017	論文	An environmental pollutant, 9,10-phenanthrenequinone, activates human TRPA1 via critical cysteines 621 and 665. Pharmacol. Res. & Persp. in Press (共著)
2017	論文	Na⁺ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells Sci. Rep. 7 (1),16988 (共著)
2017	論文	Picomolar, selective and subtype specific small-molecule inhibition of TRPC1/4/5 channels. J. Biol. Chem. 292,8158-8173頁 (共著)
2017	論文	Transcriptional repression of HER2 by ANO1 Cl^- channel inhibition in human breast cancer cells with resistance to trastuzumab. Biochem. Biophys. Res. Comm. 482,188-194頁 (共著)
2016	論文	Diclofenac, a non-steroidal anti-inflammatory drug, is an antagonist of human TRPM3 isoforms. Pharmacol Res & Persp 4 (3),e00232 (共著)
2016	論文	Downregulation of the Ca²⁺-activated K⁺ channel KCa3.1 by histone deacetylase inhibition in human breast cancer cells. Pharmacol Res & Persp 4 (2),e00228 (共著)
2016	論文	Natural and synthetic flavonoid modulation of TRPC5 channels Brit. J. Pharmacol. 173,562-574頁 (共著)
2016	論文	Recent advances in therapeutic strategies that focus on the regulation of ion channel expression. Pharmacol & Therap 160,11-43頁 (共著)
2015	論文	(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels Angewandte Chemie Int. Ed. 54,3787-3791頁 (共著)
2015	論文	Oseltamivir blocks human neuronal nicotinic acetylcholine receptor-mediated currents. Basic Clin. Pharmacol. Toxicol. 116,87-95頁 (共著)
2015	論文	Pinosylvin Inhibits TRPA1-Induced Calcium Influx In Vitro and TRPA1-Mediated Acute Paw Inflammation In Vivo. Basic Clin. Pharmacol. Toxicol. 118,238-242頁 (共著)
2014	論文	Downregulation of Ca2+-activated Cl- channel TMEM16A by the inhibition of histone deacetylase in TMEM16A-expressing cancer cells. J. Pharmacol. Exp. Therap. 351,510-518頁 (共著)
2014	論文	Human nicotinic acetylcholine receptor is a potential pharmacological target of oseltamivir. Receptors & Clin. Invest. Research Highlight 1,e360 (共著)
2014	論文	Piezo1 integration of vascular architecture with physiological force. Nature 515,279-282頁 (共著)
2014	論文	The NADPH oxidase inhibitor diphenyleneiodonium activates the human TRPA1 nociceptor. Am. J. Physiol., Cell-Physiol. 307,C384-C397頁 (共著)
2013	論文	Stimulation of human TRPA1 channels by clinical concentrations of the anti-rheumatic drug, auranofin. Am. J. Physiol., Cell-Physiol. 304,C354-C361頁 (共著)
2013	論文	TRPV4 partially participates in proliferation of human brain capillary endothelial cells. Life Sci. 92,317-324頁 (共著)
2012	論文	HIF1alpha switches on TRPA1 gene expression via a hypoxia response element-like motif to modulate cytokine release. J. Biol. Chem. 287,31962-31967頁 (共著)
2012	論文	Involvement of inositol 1,4,5-trisphosphate formation in the voltage-dependent regulation of the Ca2+ concentration in porcine coronary arterial smooth muscle cells. J. Pharmacol. Exp. Therap. 342,486-496頁 (共著)
2012	論文	Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone. Cell Calcium 55,1-11 (共著)
2011	論文	Stereo-selective inhibition of TRPC5 channels by neuroactive steroids British Journal of Pharmacology 162,1509-1520 (共著)
2011	論文	TRPC5 channel sensitivities to antioxidants and hydroxylated stilbens. Journal of Biological Chemistry 286,5078-5086 (共著)
2010	論文	Cis-isomerism and other chemical requirements of steroidal agonists and partial agonists acting at TRPM3 channels British Journal of Pharmacology 161,430-441 (共著)
2009	論文	An environmental sensor, TRPV4 is a novel regulator of intracellular Ca²⁺ in human synoviocytes Am. J. Physiol., Cell-Physiol. 297,C1082-C1090 (共著)
2009	論文	Cardiac fibroblasts have functional TRPV4 activated by 4a-phorbol 12,13-didecanoate. Life Science 85,808-814 (共著)
2008	論文	Cell-culture dependent change of Ca response of rat aortic myocytes to sphingosine-1-phosphate Journal of Pharmacological Sciences 107,434-442 (共著)
2008	論文	TRPV4-like non-selective cation currents in cultured aortic myocytes Journal of Pharmacological Sciences 108,179-789 (共著)
2006	著書	血管に対するK⁺チャネル開口薬の作用　世界に誇る日本発K⁺チャネル開口薬ニコランジル日本心電図学会学術諮問委員会,19-30 (共著)
2006	論文	A sphingosine-1-phosphate activated calcium channel controlling vascular smooth muscle cell motility Cir. Res 98,1381-1389 (共著)
2005	著書	血管平滑筋イオンチャネルとリモデリング(第2版)　イオンチャネル最前線別冊　医学の歩み,290-295 (共著)
2004	論文	Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP-Topical Review Journal of Physiology 559,685-706 (共著)
2003	論文	TRPV2 is a component of osmotically-sensitive cation channels in murine aortic myocytes. Circulation Research 93,829-838 (共著)