教員情報 - 小幡徹 | 愛知学院大学

オバタトオル OBATA Tohru
小幡徹

所属薬学部生体有機化学

職種准教授

著書・論文歴
2023/10/23	論文	Nucleophile-Triggered π-Topological Transformation: A New Synthetic Approach to Near-Infrared-Emissive Rhodamines Chemistry – A European Journal 29 (59),e202301969 (共著)
2022/07/19	論文	Visualization of the photodegradation of a therapeutic drug by chemometric-assisted fluorescence spectroscopy RSC Advances 12 (32),20714-20720頁 (共著)
2022/06/25	論文	Bridged eosin Y: a visible and near-infrared photoredox catalyst Chemical Communications 58 (56),7825-7828頁 (単著)
2021/05/01	論文	Structure-activity Relationship of Indomethacin Derivatives as IDO1 Inhibitors Anticancer Research 41 (5),2287-2296頁 (共著)
2021/03/01	著書	コンパス分子生物学改訂第3版創薬・テーラーメイド医療に向けて (共著)
2021	論文	Enhancing Effect of Novel Schiff Base Derivatives, UTX-134 and UTX-135, on 5-Aminolevulinic Acid-based Photodynamic Therapy ALA-Porphyrin Science 10 (1),1-14頁 (共著)
2020/05/20	論文	Synthesis and anticancer activity of bis(2-arylimidazo[1,2-a]pyridin-3-yl) selenides and diselenides: the copper-catalyzed tandem C―H selenation of 2-arylimidazo[1,2-a]pyridine with selenium Beilstein J. Org. Chem 16,1075-1083頁 (共著)
2018/01	論文	Synthesis, antitumor activity, and cytotoxicity of 4-substituted 1-benzyl-5-diphenylstibano-1H-1,2,3-triazoles Bioorganic & Medicinal Chemistry Letters 28 (2),152-154頁 (共著)
2017/07	論文	A versatile synthesis of triarylantimony difluorides by fluorination of triarylstibanes with nitrosyl tetrafluoroborate and their antitumor activity Journal of Fluorine Chemistry 199,1-6頁 (共著)
2016/12	論文	Structure-cytotoxicity relationship of methacrylate-based resin monomers as evaluated by an anti-oxidant responsive element-luciferase reporter assay Dental Materials Journal 35 (6),946-951頁 (共著)
2016/07	論文	Synthesis and Optical Properties of Fluorine-Containing Phthalocyanine Conjugated with Glucofuranose and its Application to Photo-Dynamic Therapy Journal of the Japan Society of Colour Material 89 (7),213-218頁 (共著)
2016/04	論文	Synthesis, structural characterization and antitumor activity of 2-(di-p-tolylstibano)- and 2-(di-p-tolylbismuthano)-N-p-tolylbenzamide Journal of Organometallic Chemistry 807,17-21頁 (共著)
2015/06	論文	Design, synthesis, spectral investigations and biological activity of fluorinated phthalocyanine conjugated with galactose and comparison to its non-fluorinated counterpart Journal of Fluorine Chemistry 174,137-141頁 (共著)
2015/01	論文	Photodynamic Therapy Using Novel Zinc Phthalocyanine Derivatives and a Diode Laser for Superficial Tumors in Experimental Animals Journal of Cancer Therapy 6 (1),53-61頁 (共著)
2014/05	論文	Improvement of the antitumor activity of poorly soluble sapacitabine (CS-682) by using Soluplus(R) as a surfactant Biol Pharm Bull 37 (5),802-807頁 (共著)
2013/10	論文	The Role of Thymidylate Synthase in Pemetrexed-Resistant Malignant Pleural Mesothelioma Cells Journal of Cancer Therapy 4 (6),1052-1059頁 (共著)
2012/08	論文	Design and Synthesis of Indomethacin Analogues That Inhibit P-Glycoprotein and/or Multidrug Resistant Protein without Cox Inhibitory Activity J Med Chem 55 (18),8152-8163 (共著)
2012/05	論文	がん光線力学療法の新たな展開-光増感剤からのアプローチ- 光アライアンス 5月号,41-44 (共著)
2011/03	論文	Indomethacin Analogues that Enhance Doxorubicin Cytotoxicity in Multidrug Resistant Cells without Cox Inhibitory Activity ACS Medicinal Chemistry Letters 2 (5),353-357 (共著)
2010/10	論文	Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogues in vitro and in vivo Drug Metabolism and Disposition 8 (10),1814-1819 (共著)
2009/07	論文	Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides Bioorg Med Chem Lett 19 (14),3973-3976 (共著)
2008	論文	新規抗腫瘍性シトシンヌクレオシドの開発愛知学院大学薬学会誌 1,1-8 (共著)
2007/10	論文	Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides Cancer Science 98 (10),1633-1637 (共著)
2007/01	論文	Recent advances in the treatment of peritoneal dissemination of gastrointestinal cancers by nucleoside antimetabolites Cancer Sci. 98 (1),11-18 (共著)
2007	論文	Development of an antitumor adenosine analog, 3'-ethynyladenosine Nucleosides Nucleotides Nucleic Acids 26 (6-7),691-694 (共著)
2006/06	論文	In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer Oncol Rep 15 (6),1533-1539 (共著)
2004/02	論文	Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2α Kinase GCN2 The Journal of Organic Chemistry 69 (2),314-326 (共著)
1996/04	著書	腹膜播種 (共著)