教員情報 - 濵村和紀 | 愛知学院大学

ハマムラカズノリ HAMAMURA Kazunori
濵村和紀

所属歯学部薬理学

職種教授

著書・論文歴
2024	著書	現代歯科薬理学　第7版,351-360頁 (共著)
2024	論文	Globo-series Gb4 activates ERK and promotes the proliferation of osteoblasts. J. Oral Biosci. 66 (1),41-48頁 (共著)
2024	論文	Regulation of glycosylation in bone metabolism. Int. J. Mol. Sci. 25 (7),3568 (共著)
2023	著書	Glycosignals in Cancer: Molecular Assembly and Recognition, Second Edition,151-169頁 (共著)
2023	著書	ポイントがよくわかるシンプル歯科薬理学　第3版 (共著)
2022	論文	Attenuation of bone formation through a decrease in osteoblasts in mutant mice lacking the GM2/GD2 synthase gene. Int. J. Mol. Sci. 23 (16),9044 (共著)
2022	論文	Ganglioside GD2 enhances the malignant phenotypes of melanoma cells by cooperating with integrins. Int. J. Mol. Sci. 23 (1),423 (共著)
2022	論文	Orthodontic tooth movement-activated sensory neurons contribute to enhancing osteoclast activity and tooth movement through sympathetic nervous signalling. Eur. J. Orthod. 44 (4),404-411頁 (共著)
2022	論文	Signaling domains of cancer-associated glycolipids. Glycoconj. J 39 (2),145-155頁 (共著)
2021	論文	Contribution of glucosylceramide synthase to the proliferation of mouse osteoblasts. In Vivo 35 (6),3111-3123頁 (共著)
2021	論文	Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis. J. Pharmacol. Sci. 147 (3),294-304頁 (共著)
2021	論文	Lewis y expressed in oral squamous cell carcinoma attenuates malignant properties via down-regulation of EGF signaling. Anticancer Res. 41 (4),1821-1830頁 (共著)
2021	論文	Suppression of alveolar bone resorption by salubrinal in a mouse model of periodontal disease. Life Sci. 284,119938 (共著)
2020	論文	Effects of glucocorticoids on diurnal variations in experimental tooth movement. J. Hard Tissue Biol. 29 (4),231-238頁 (共著)
2020	論文	SSEA-3 and 4 are not essential for the induction or properties of mouse iPS cells. J. Oral Sci. 62 (4),393-396頁 (共著)
2019	著書	ポイントがよくわかるシンプル歯科薬理学　第2版 (共著)
2019	論文	Deficiency of GD3 synthase in mice resulting in the attenuation of bone loss with aging. Int. J. Mol. Sci. 20 (11),2825 (共著)
2019	論文	Deletion of Gb3 synthase in mice resulted in the attenuation of bone formation via decrease in osteoblasts. Int. J. Mol. Sci. 20 (18),4619 (共著)
2019	論文	eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice. Cell Death Dis. 10 (12),921 (共著)
2019	論文	New era of research on cancer-associated glycosphingolipids. Cancer Sci. 110 (5),1544-1551頁 (共著)
2019	論文	Systemic administration of low-dose naltrexone increases bone mass due to blockade of opioid growth factor receptor signaling in mice osteoblasts. Life Sci. 224,232-240頁 (共著)
2018	論文	Alpha 1B-adrenergic receptor signaling contributes to experimental tooth movement. Aichi Gakuin Dent. Sci. 31,31-41頁 (共著)
2018	論文	Conditioned medium from rat dental pulp reduces the number of osteoclasts via attenuation of adhesiveness in osteoclast precursors. J. Oral. Sci. 60 (3),352-359頁 (共著)
2018	論文	Differential roles of gangliosides in malignant properties of melanomas. PLoS ONE 13 (11),e0206881 (共著)
2018	論文	Suppression of osteoclastogenesis via alpha2-adrenergic receptors. Biomed. Rep. 8 (5),407-416頁 (共著)
2018	論文	カテコラミンと骨代謝内分泌・糖尿病・代謝内科 46 (6),434-438頁 (共著)
2017	著書	ポイントがよくわかるシンプル歯科薬理学 (共著)
2017	著書	歯科衛生士テキスト　最新薬理学 ―疾病の成り立ち及び回復過程の促進― (共著)
2017	論文	Bidirectional communication between sensory neurons and osteoblasts in an in vitro co-culture system. FEBS Lett. 591 (3),527-539頁 (共著)
2017	論文	Glycosylation is involved in malignant properties of cancer cells. Cancer Transl. Med. 3 (6),209-213頁 (共著)
2017	論文	Reduction in migratory phenotype in a metastasized breast cancer cell line via downregulation of S100A4 and GRM3. Sci. Rep. 7 (1),3459 (共著)
2016	論文	A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3. Biochim. Biophys. Acta Gen. Subj. 1860 (8),1753-1763頁 (共著)
2016	論文	alpha 1B-adrenergic receptor signaling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein delta expression in osteoblasts. Br. J. Pharmacol. 173 (6),1058-1069頁 (共著)
2016	論文	Guanabenz downregulates inflammatory responses via eIF2 alpha dependent and independent signaling. Int. J. Mol. Sci. 17 (5),674 (共著)
2016	論文	Pharmacological blockade of 5-HT2B receptor signaling impairs bone formation in mice. Aichi Gakuin Dent. Sci. 29,1-7頁 (共著)
2016	論文	Role of miR-222-3p in c-Src-mediated regulation of osteoclastogenesis. Int. J. Mol. Sci. 17 (2),240 (共著)
2016	論文	Salubrinal improves mechanical properties of the femur in osteogenesis imperfecta mice. J. Pharmacol. Sci. 132 (2),154-161頁 (共著)
2016	論文	Suppression of osteoclastogenesis via upregulation of Zfyve21 and Ddit4 by salubrinal and guanabenz. Oral Therap. Pharmacol. 35 (3),127-135頁 (共著)
2016	論文	糖鎖修飾による癌の悪性形質制御機構口腔組織培養学会誌 25 (2),9-17頁 (共著)
2015	論文	Attenuation of inflammatory arthritis through downregulating Dusp2 by salubrinal. Macrophage 2 (1),e650 (共著)
2015	論文	Chondroprotective effects of salubrinal in a mouse model of osteoarthritis. Bone Joint Res. 4 (5),84-92頁 (共著)
2015	論文	Enhancement of osteoblastogenesis and suppression of osteoclastogenesis by inhibition of de-phosphorylation of eukaryotic translation initiation factor 2 alpha. Receptor Clin. Invest. 2 (1),e493 (共著)
2015	論文	In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz. Cell. Signal. 27 (2),353-362頁 (共著)
2015	論文	MSC transplantation improves osteopenia via epigenetic regulation of notch signaling in Lupus. Cell Metab. 22 (4),606-618頁 (共著)
2015	論文	Potential therapeutic applications of salubrinal for skeletal diseases and beyond. J. Nat. Sci. 1 (8),e151 (共著)
2015	論文	Salubrinal acts as a Dusp2 inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. Cell. Signal. 27 (4),828-835頁 (共著)
2015	論文	Suppressed invasive and migratory behaviors of SW1353 chondrosarcoma cells through the regulation of Src, Rac1 GTPase, and MMP13. Cell. Signal. 27 (12),2332-2342頁 (共著)
2014	論文	Attenuation of malignant phenotypes of breast cancer cells through eIF2 alpha-mediated downregulation of Rac1 signaling. Int. J. Oncol. 44 (6),1980-1988頁 (共著)
2014	論文	Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis. Cell. Signal. 26 (11),2358-2369頁 (共著)
2013	論文	Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells. BMC Musculoskelet. Disord. 14 (1),197 (共著)
2013	論文	In Vitro and in Silico analysis of ADAMTS5 transcription in human chondrocytes. J. Arthritis 2 (1),111 (共著)
2013	論文	Knee loading reduces MMP13 activity in the mouse cartilage. BMC Musculoskelet. Disord. 14 (1),312 (共著)
2013	論文	Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x. Glycoconj. J. 30 (6),585-597頁 (共著)
2013	論文	Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes. J Musculoskelet. Neuronal. Interact. 13 (3),372-379頁 (共著)
2013	論文	Salubrinal reduces expression and activity of MMP13 in chondrocytes. Osteoarthritis Cartilage 21 (5),764-772頁 (共著)
2013	論文	Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha. J. Bone Miner. Metab. 31 (6),618-628頁 (共著)
2013	論文	Trimeric Tn antigen on Syndecan-1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin alpha 5 beta 1 and matrix metalloproteinase 9. J. Biol. Chem. 288 (33),24264-24276頁 (共著)
2012	論文	Disialyl gangliosides enhance tumor phenotypes with differential modalities. Glycoconj. J. 29 (8-9),579-584頁 (共著)
2012	論文	Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3. Cancer Sci. 103 (9),1656-1664頁 (共著)
2012	論文	Fine tuning of cell signals by glycosylation. J. Biochem. 151 (6),573-578頁 (共著)
2012	論文	Hydroxyapatite modulates mRNA expression profiles in cultured osteocytes. Cell. Mol. Bioeng. 5 (2),217-226頁 (共著)
2012	論文	pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen. Biochem. Biophys. Res. Commun. 419 (1),7-13頁 (共著)
2012	論文	Proteomic analysis of ganglioside-associated membrane molecules: Substantial basis for molecular clustering. Proteomics 12 (21),3154-3163頁 (共著)
2012	論文	RhoA-mediated signaling in mechanotransduction of osteoblasts. Connect. Tissue Res. 53 (5),398-406頁 (共著)
2012	論文	Salubrinal promotes healing of surgical wounds in rat femurs. J. Bone Miner. Metab. 30 (5),568-579頁 (共著)
2012	その他	糖鎖修飾によるシグナル伝達の制御実験医学　増刊 30 (5),771-776頁 (共著)
2011	論文	Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3. J. Biol. Chem. 286 (21),18526-18537頁 (共著)
2011	論文	Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: Induction of the lipogenic pathway by a melanoma antigen. Cancer Res. 71 (14),4989-4997頁 (共著)
2010	著書	コールドスプリングハーバー　糖鎖生物学　第2版,75-84頁 (共著)
2010	論文	ECM-dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK, and p38 MAPK of osteoblast-like cells. Cell Biol. Int. 34 (10),1005-1012頁 (共著)
2010	論文	Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains. J. Biol. Chem. 285 (35),27213-27223頁 (共著)
2010	論文	GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line. Cancer Sci. 101 (9),2039-2047頁 (共著)
2010	その他	分子標的薬からみた我が国における創薬日本臨床 68 (10),1797-1802頁 (共著)
2009	著書	第3の生命鎖　糖鎖の謎が今、解かる,85-94頁 (共著)
2009	論文	Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum. Arch. Oral Biol. 54 (3),279-286頁 (共著)
2009	論文	Potential applications of pulsating joint loading in sports medicine. Exerc. Sport Sci. Rev. 37 (1),52-56頁 (共著)
2008	論文	Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3. Biochem. Biophys. Res. Commun. 373 (1),14-19頁 (共著)
2008	論文	Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells. Biochim. Biophys. Acta 1780 (3),513-519頁 (共著)
2008	論文	IGF2-driven PI3 Kinase and TGF beta Signaling pathways in chondrogenesis. Cell Biol. Int. 32 (10),1238-1246頁 (共著)
2008	論文	Microarray analysis of thapsigargin-induced stress to endoplasmic reticulum of mouse osteoblasts. J. Bone Miner. Metab. 26 (3),231-240頁 (共著)
2008	論文	Molecules in the signaling pathway activated by gangliosides can be targets of therapeutics for malignant melanomas. Proteomics 8 (16),3312-3316頁 (共著)
2008	論文	PEG attachment to osteoblasts enhances mechanosensitivity. Biomed. Mater. 3 (2),25017 (共著)
2008	その他	癌細胞の形質を創出する細胞膜近傍の分子複合体蛋白質核酸酵素 53 (12),1547-1551頁 (共著)
2007	論文	Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties. Cancer Sci. 98 (4),512-520頁 (共著)
2007	論文	Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling. FEBS Lett. 581 (9),1769-1774頁 (共著)
2006	論文	Biosignals modulated by tumor-associated carbohydrate antigens: Novel targets for cancer therapy. Ann. N. Y. Acad. Sci. 1086,185-198頁 (共著)
2005	論文	Differential enhancing effects of alpha 2,8-sialyltransferase on the cell proliferation and mobility. Int. J. Oncol. 26,337-344頁 (共著)
2005	論文	Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc. Natl. Acad. Sci. USA. 102 (31),11041-11046頁 (共著)
2005	論文	GM1 expression in H-ras-transformed NIH3T3 results in the suppression of cell proliferation inducing the partial transfer of activated H-ras from non-raft to raft fraction. Int. J. Oncol. 26,897-904頁 (共著)
2005	論文	Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: Roles of anoikis. J. Biol. Chem. 280 (33),29828-29836頁 (共著)